In vitro research has many advantages over in vivo research (cheaper, faster, tighter control of chemical and physical environment, etc.). However, isolated and cultivated primary cells differ from the corresponding cell type in an organism, limiting the value of in vitro data to predict in vivo behaviour. A major reason for this divergence is that in vitro experiments do not replicate the mechanical and electrical environment of cells in an organism. MEASSuRE addresses this weakness by reproducing the mechanical (radial, uniaxial) and electrical environment of cells in vivo in a controlled environment in vitro.
With MEASSuRE systems researchers do not need to choose between electrical and mechanical biophysical cues for in vitro research. The cell and tissue cultures are grown on silicone substrates with embedded microelectrodes.
MEASSuRE will serve as a platform to enable fundamentally improved methods to investigate physiological and pathological stretch of cells in a controlled in vitro environment. In addition, MEASSuRE allows optical imaging (optional) of the cells throughout the stretching process for verification of the tissue strain and to detect morphological changes in the tissue.
The MEASSuRE systems (MEASSuRE-Mini, Premium and MEASSuRE-X) as well as all other products from BMSEED can be purchased through the exclusive distributor for Europe, Dunn Labortechnik.
Please contact us for detailed information or visit our website: www.dunnlab.de
Dunn Labortechnik GmbH
Thelenberg 6
53567 Asbach
Telefon: +49 (2683) 43094
Telefax: +49 (2683) 42776
http://www.dunnlab.de
Produktmanager
Telefon: +49 (2683) 430-94
Fax: +49 (2683) 427-76
E-Mail: Kevin.denkmann@dunnlab.de
